Danish nobleman and astronomer Tycho Brahe was notoriously eccentric. He had a dwarf who sat under the table during dinner, and a tame pet moose. After losing the tip of his nose in a duel, he wore a prosthetic nose made from silver and gold.
Surprisingly, it was the constraints of polite society that killed him. During one particularly long banquet in 1601, Tyco held his water so long he strained his bladder. It is said he later developed an infection killed him, although later analysis showed signs of mercury poisoning.